Purpose: To compare Distance Visual Acuity (DVA) in Non-Dominant Eye (NDE) achieved with monovision using contact lenses with post-operative bilateral PresbyLasik Custom Q and to confirm laser-induced multifocality in presbyopic and hyperopic patients. Method: Prospective intra-individually controlled superiority study including presbyopic hyperopic patients led between January 2018 and February 2019. Classical monovision was simulated with contact lenses aiming at myopic defocus in NDE whereas an emmetropic correction was targeted in Dominant Eye (DE). The visual acuities were measured first with contact lenses then 1, 3 and 6 months post-operatively. The NDE is targeted, an aspheric profile by inducing a negative spherical aberration and myopic defocus and in DE a central emmetropia with positive spherical aberration. Corneal asphericity (Q-Factor), corneal spherical aberration (C4, 0 and C6, 0), were measured in all patients before and after surgery.