Cardiovascular Diseases (CVD), the leading cause of death worldwide and its principal manifestations, are characterized by atherosclerotic plaques and thrombosis, chronic inflammatory consequences. Finding non- or minimally invasive treatment options for these effects on the coronary network is crucial and has turned into a cross-disciplinary issue. As a result, research is currently being done on smart drug delivery systems, which are specifically based on micro- and nanoparticles, as a viable way to provide non- or minimally invasive therapeutic processes. In contrast to traditional interventional cardiology procedures, computational models enable us to investigate, devise, and anticipate treatment plans based on smart drug delivery devices with less time and expense. Additionally, the improvement and development of computer techniques and models have produced a vast and useful understanding of patient-specific medication design and therapy approaches.
